The building currently known as The Hoxie House was originally built in 1818 by shipmaster and trader Nathaniel Clift as the U.S. Hotel. Lodging was offered on the second and third floors, and commercial business was conducted on the first.

After a fire destroyed the hotel in 1858, prominent businessman Benjamin F. Hoxie rebuilt the property, and in 1861, The Hoxie Hotel opened its doors to the public. Mr. Hoxie’s vision was to create a luxury hotel that would attract an upscale clientele and help transform Mystic into a summer resort destination.

Destroyed again by fire in 1975, but rebuilt in 2002 as part of The Whaler’s Inn, The Hoxie House has played host to a former president, celebrities, and diverse travelers captivated by its picturesque views of the Mystic River and Bascule Drawbridge. Most recently renovated in 2018, the Hoxie House is home to eight deluxe guest rooms and the hotel lobby.

Named after nearby fishing villages, The Stonington and Noank Houses were built in the early 1980s to accommodate an increasing number of visitors to Mystic. The addition of rooms with two Queen beds was popular with families visiting The Mystic Seaport and Aquarium, as well as with groups planning reunions and get-togethers.

The Stanton House is the Inn’s newest addition and a tribute to the legacy of women in Mystic’s history. Opened under the leadership of the Heidenreich family and President Amanda Arling-Carlson, it was named after Fanny Stanton, wife of 19th-century mill owner Joseph Cottrell. While Cottrell’s lumber mill helped shape the town’s industrial past, Stanton’s name—quietly carried on a side street nearby—represents the often-overlooked women whose influence anchored the community. Rooted in that history, The Stanton House blends timeless New England architecture with modern luxury, offering private elevator access, suites with river views, and interiors designed to reflect both elegance and resilience.